There are two major types: primary osteoporosis and secondary osteoporosis.
Primary osteoporis is more common and is not assocated with an undrlying pathologic condition. It accures in both genders at any age but most often affects women after menopause adn men in their later years.
Secondary osteoporosis results from an associated medical condition, such as hyperparathyrodism; long-term drug therapy, such as with corticosteroids; or prolonged immobility, such as that seen with spinal cord injury.
Treatment of the secondary type is directed toward the cause of the osteoporosis when possible.
Wednesday, 26 December 2007
Pathophysiology of Ostoeporosis
Bone is a dynamic tissue. Throughout a person's life span, nw bone is formed by osteoblastic activity, whereas old bone is resorbed activity; this process is known as bone modeling. BMD determines bone strength and peaks between 30 and 35 years of age. After the peak years, bone resoption activity exceeds bone-building activity, and bone density decrease. Trabecular, or cancellous (spongy), bone is los first, followed by loss of cortical cortical (compact) bone.
BMD decreses rapidly in postmenospausal women as serus estrogen level diminish. Approximatly 40% to 45% of a woman's bone mass is lost during herl life span. It is estimated that 50% of all women older than 65 years of age have symptomatic osteoporosis.
More than half of all Caucasion women have at least one osteoporotic fracture during their lifetime. Men also develop osteoporosis and resulting frctures. Studies have shown that although men are less likely than women to experience a fracture, the lifetime ris of fracture is 13% to 25% (Bilezikian, 1990)
BMD decreses rapidly in postmenospausal women as serus estrogen level diminish. Approximatly 40% to 45% of a woman's bone mass is lost during herl life span. It is estimated that 50% of all women older than 65 years of age have symptomatic osteoporosis.
More than half of all Caucasion women have at least one osteoporotic fracture during their lifetime. Men also develop osteoporosis and resulting frctures. Studies have shown that although men are less likely than women to experience a fracture, the lifetime ris of fracture is 13% to 25% (Bilezikian, 1990)
Tuesday, 18 December 2007
Osteoporosis
OVERVIEW
Osteoporosis us a metabolic disease in which bone deminerazation results in decreased density and subsquent fractures. The wrist, hip, and vertebral column are most often affected.
The World Health Organization has developed a standart for osteoporosis diagnosis base on -bone mineral density (BMD) value using T-scores. A T-score is the number of stard deviations above or below the average BMD. Low bone mass (osteopenia) is present when T-score is between -1 and -2.5. Osteoporosis is posmenopausal women is defined as a BMD T-score at or below -2.5(Ott, 1999).
Osteoporosis us a metabolic disease in which bone deminerazation results in decreased density and subsquent fractures. The wrist, hip, and vertebral column are most often affected.
The World Health Organization has developed a standart for osteoporosis diagnosis base on -bone mineral density (BMD) value using T-scores. A T-score is the number of stard deviations above or below the average BMD. Low bone mass (osteopenia) is present when T-score is between -1 and -2.5. Osteoporosis is posmenopausal women is defined as a BMD T-score at or below -2.5(Ott, 1999).
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